APPROACHING THE BLACK HOLE BY NUMERICAL SIMULATIONS

Approaching the Black Hole by Numerical Simulations

Black holes represent extreme conditions of physical laws.Predicted about a century ago, they are now accepted as astrophysical reality by most of the scientific community.Only recently has more direct evidence of their existence been found—the detection of gravitational waves from black hole mergers and of the shadow of a supermassive black

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Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells

Urea cycle disorders are incurable ashy bines protein powder enzymopathies that affect nitrogen metabolism and typically lead to hyperammonemia.Arginase deficiency results from a mutation in Arg1, the enzyme regulating the final step of ureagenesis and typically results in developmental disabilities, seizures, spastic diplegia, and sometimes death.

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